Repository of Research and Investigative Information

Repository of Research and Investigative Information

Zahedan University of Medical Sciences

Kidney Function Tests in Children with Beta-Thalassemia Minor in Zahedan, Southeast of Iran

(2011) Kidney Function Tests in Children with Beta-Thalassemia Minor in Zahedan, Southeast of Iran. Iranian Journal of Kidney Diseases. pp. 201-203. ISSN 1735-8582

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Official URL: <Go to ISI>://WOS:000297130100010

Abstract

There is little information regarding kidney function in patients with beta-thalassemia minor. In this study we investigated kidney function tests in 50 children with beta-thalassemia minor (22 boys and 28 girls). Twenty-four-hour urine samples were collected and analyzed for sodium, potassium, calcium, magnesium, creatinine, phosphate, uric acid, protein, and beta 2-microglobulin. Blood samples were obtained for hematologic and biochemical analyses including complete blood count, serum ferritin, sodium, potassium, calcium, phosphate, magnesium, creatinine, and uric acid. This group of children with beta-thalassemia showed some evidence of tubulopathy such as proteinuria (32), beta 2-microglobulin excretion (36), calciuria (4), phosphaturia (4), and uricosuria (20). Our findings support the existence of renal tubular dysfunction in beta-thalassemia minor. However, further studies in large series are needed to shed light on the possible relation of these two distinct diseases.

Item Type: Article
Keywords: beta-thalassemia kidney function tests proteinuria renal tubular function iron-deficiency anemia early markers dysfunction Urology & Nephrology
Page Range: pp. 201-203
Journal or Publication Title: Iranian Journal of Kidney Diseases
Journal Index: ISI
Volume: 5
Number: 3
ISSN: 1735-8582
Depositing User: خانم مهدیه رضائی پور
URI: http://eprints.zaums.ac.ir/id/eprint/2706

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