Repository of Research and Investigative Information

Repository of Research and Investigative Information

Zahedan University of Medical Sciences

The status of serum procalcitonin in sepsis and non-infectious systemic inflammatory response syndrome

(2010) The status of serum procalcitonin in sepsis and non-infectious systemic inflammatory response syndrome. African Journal of Microbiology Research. pp. 2632-2634. ISSN 1996-0808

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Official URL: <Go to ISI>://WOS:000285848100030

Abstract

Procalcitonin (PCT) is a marker of the inflammatory response to infection and not released in viral disease. The aim of the present study was to determine the level of PCT in sepsis and non-infectious systemic inflammatory response syndrome (SIRS). We determined the level of serum PCT in 50 sepsis and 50 non-infectious SIRS cases, using semiquantitative PCT-Q kit. The frequency of PCT positivity was significantly higher in sepsis than non-infectious SIRS (P < 0.001). Using cut off value of 2 ng/ml for PCT, the sensitivity, specificity, positive predictive value and negative predictive value for serum PCT in distinguishing sepsis from non-infectious SIRS were 88.0, 90.0, 89.8 and 88.2, respectively. The serum PCT is a reliable marker for distinguishing sepsis from non-infectious SIRS in association with clinical judgment and other paraclinical findings.

Item Type: Article
Keywords: Sepsis SIRS procalcitonin intensive-care units infection marker Microbiology
Page Range: pp. 2632-2634
Journal or Publication Title: African Journal of Microbiology Research
Journal Index: ISI
Volume: 4
Number: 23
ISSN: 1996-0808
Depositing User: خانم مهدیه رضائی پور
URI: http://eprints.zaums.ac.ir/id/eprint/2733

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