Repository of Research and Investigative Information

Repository of Research and Investigative Information

Zahedan University of Medical Sciences

Serum adenosine deaminase activity in gestational diabetes mellitus and normal pregnancy

(2010) Serum adenosine deaminase activity in gestational diabetes mellitus and normal pregnancy. Archives of Gynecology and Obstetrics. pp. 623-626. ISSN 0932-0067

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Official URL: <Go to ISI>://WOS:000275398300007

Abstract

To our knowledge, there is no report regarding adenosine deaminase activity (ADA) in gestational diabetes mellitus (GDM). The aim of the present study was to investigate the level of serum ADA activity in normal pregnancy, GDM and normal non-pregnant women. The serum catalytic concentration of ADA was measured in samples of 20 GDM, 40 normal pregnant and 20 non-pregnant healthy women. Adenosine deaminase activity was significantly higher in GDM (24.30 +/- A 8.04 IU/L) and pregnant women (23.88 +/- A 8.66 IU/L) than those of normal non-pregnant individuals (11.85 +/- A 3.23 IU/L) (P < 0.0001), but the ADA level was not significantly different from GDM and normal pregnant women (P = 0.97). Adenosine deaminase activity was significantly higher in GDM and pregnant individuals than normal group in this study. Previous reports in this field are contentious; therefore, ADA activity could be regulated in different population by immunologic and genetic factors.

Item Type: Article
Keywords: Adenosine deaminase Gestational diabetes mellitus Pregnancy insulin system women preeclampsia adipocytes acid th1 Obstetrics & Gynecology
Page Range: pp. 623-626
Journal or Publication Title: Archives of Gynecology and Obstetrics
Journal Index: ISI
Volume: 281
Number: 4
Identification Number: https://doi.org/10.1007/s00404-009-1148-3
ISSN: 0932-0067
Depositing User: خانم مهدیه رضائی پور
URI: http://eprints.zaums.ac.ir/id/eprint/2767

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