Repository of Research and Investigative Information

Repository of Research and Investigative Information

Zahedan University of Medical Sciences

Usefulness of the tail-flick reflex in the prognosis of functional recovery in paraplegic rats

(2008) Usefulness of the tail-flick reflex in the prognosis of functional recovery in paraplegic rats. Surgical Neurology. pp. 323-325. ISSN 0090-3019

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Official URL: <Go to ISI>://WOS:000258772100015

Abstract

Background: This study examines whether return of the TFR is predictive of locomotor recovery after complete SCI in rats. Methods: We evaluated TFRs in 39 adult female rats. The spinal cords of rats were compressed at T9 with Yasargil clips. The TFR and BBB were performed on each rat after surgery, at 24 hours, on the fourth day, and weekly. Results: On the first day, all of these 39 rats had a BBB score of 0. Of these, the TFR in response to tail pinch was present in 16 (41) cases. Of the 16 rats, 12 (75) showed a gradual increase in BBB scores during subsequent weeks. However, in the 23 animals in which the TFR was absent, none showed improvement in BBB score or return of hindlimb movements. Conclusions: We conclude that after complete SCI, return of the TFR correlates strongly with return of motor activity. (c) 2008 Elsevier Inc. All rights reserved.

Item Type: Article
Keywords: spinal cord injuries reflex rats motor activity stimulation Neurosciences & Neurology Surgery
Page Range: pp. 323-325
Journal or Publication Title: Surgical Neurology
Journal Index: ISI
Volume: 70
Number: 3
Identification Number: https://doi.org/10.1016/j.surneu.2007.05.056
ISSN: 0090-3019
Depositing User: خانم مهدیه رضائی پور
URI: http://eprints.zaums.ac.ir/id/eprint/2843

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