Repository of Research and Investigative Information

Repository of Research and Investigative Information

Zahedan University of Medical Sciences

Lipid composition of spermatozoa in normozoospermic and asthenozoospermic males

(2007) Lipid composition of spermatozoa in normozoospermic and asthenozoospermic males. Prostaglandins Leukotrienes and Essential Fatty Acids. pp. 45-50. ISSN 0952-3278

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Official URL: <Go to ISI>://WOS:000249545500007

Abstract

Introduction: Lipids play an important role in the structural and functional activity of spermatozoa. We investigated the phospholipids composition and fatty acid-bound phospholipid of spermatozoa from asthenozoospermic and normozoospermic men. Patients and methods: Semen samples were analyzed in 15 asthenozoospermic and eight normozoospermic subjects and the sperm phospholipids and fatty acids were determined using high performance thin layer chromatography and gas chromatography, respectively. Results: The most abundant (mean SE) phospholipids in normozoospermic and asthenozoospermic samples were phosphatidylethanolamine (70.9 +/- 11.5 and 44.2 +/- 8.5nmol/10(8) spermatozoa, respectively) and phosphatidylcholine (58.6 +/- 9.5 and 34.6 +/- 3.2 nmol/10(8) spermatozoa, respectively). Compared to normozoospermic samples, asthenozoospermic samples showed lower levels of polyunsaturated fatty acids (PUFA; p < 0.01) and higher levels of saturated fatty acids (SFA; p < 0.05). Discussion: Changes in content of phospholipids and its fatty acid composition of spermatozoa may be related to infertility in asthenozoospermic males. (c) 2007 Elsevier Ltd. All rights reserved.

Item Type: Article
Keywords: fatty-acid-composition seminal plasma phospholipid-composition docosahexaenoic acid human sperm serum chromatography maturation generation membrane Biochemistry & Molecular Biology Cell Biology Endocrinology & Metabolism
Page Range: pp. 45-50
Journal or Publication Title: Prostaglandins Leukotrienes and Essential Fatty Acids
Journal Index: ISI
Volume: 77
Number: 1
Identification Number: https://doi.org/10.1016/j.plefa.2007.07.001
ISSN: 0952-3278
Depositing User: خانم مهدیه رضائی پور
URI: http://eprints.zaums.ac.ir/id/eprint/2887

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