Repository of Research and Investigative Information

Repository of Research and Investigative Information

Zahedan University of Medical Sciences

Effects of vacuum-compression therapy on healing of diabetic foot ulcers: Randomized controlled trial

(2007) Effects of vacuum-compression therapy on healing of diabetic foot ulcers: Randomized controlled trial. Journal of Rehabilitation Research and Development. pp. 631-636. ISSN 0748-7711

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Official URL: <Go to ISI>://WOS:000251744800002

Abstract

A single-blind, randomized controlled trial was conducted to evaluate vacuum-compression therapy (VCT) for the healing of diabetic foot ulcers. Eighteen diabetic patients with foot ulcers were recruited through simple non-probability sampling. Subjects were randomly assigned to either an experimental or a control group. Before and after intervention, the foot ulcer surface area was estimated stereologically, based on Cavalieri's principle. The experimental group was treated with VCT in addition to conventional therapy for 10 sessions. The control group received only conventional therapy, including debridement, blood glucose control agents, systemic antibiotics, wound cleaning with normal saline, offloading (pressure relief), and daily wound dressings. The mean foot ulcer surface area decreased from 46.88 +/- 9.28 mm(2) to 35.09 +/- 4.09 mm(2) in the experimental group (p = 0.006) and from 46.62 +/- 10.03 mm(2) to 42.89 +/- 8.1 mm(2) in the control group (p = 0.01). After treatment, the experimental group significantly improved in measures of foot ulcer surface area compared with the control group (p = 0.024). VCT enhances diabetic foot ulcer healing when combined with appropriate wound care.

Item Type: Article
Keywords: Cavalieri's principle conventional therapy diabetic foot ulcer healing randomized controlled trial rehabilitation stereology ulcer area vasotrain VCT intermittent pneumatic compression limb ischemia stereology efficiency wounds experience management risk Rehabilitation
Page Range: pp. 631-636
Journal or Publication Title: Journal of Rehabilitation Research and Development
Journal Index: ISI
Volume: 44
Number: 5
Identification Number: https://doi.org/10.1682/jrrd.2007.01.0002
ISSN: 0748-7711
Depositing User: خانم مهدیه رضائی پور
URI: http://eprints.zaums.ac.ir/id/eprint/2901

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