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Repository of Research and Investigative Information

Zahedan University of Medical Sciences

Inpatient Buprenorphine-Assisted Withdrawal for Treatment of Vulnerable Adolescents with Opioids Use Disorder in Zahedan, Iran: An Observational Study

(2019) Inpatient Buprenorphine-Assisted Withdrawal for Treatment of Vulnerable Adolescents with Opioids Use Disorder in Zahedan, Iran: An Observational Study. International Journal of High Risk Behaviors and Addiction. ISSN 2225-872x

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Abstract

Background: There are limited data supporting the effectiveness of buprenorphine treatment for opioid use disorder among adolescents. Objectives: The aim of this study was to investigate the outcomes of using buprenorphine for inpatient medically assisted withdrawal of vulnerable adolescents with opioid use disorder. Methods: From November 2015 to March 2016, 12 consecutive vulnerable adolescents due to working or living in streets were admitted to the Child and Adolescent Psychiatric Ward of Ali Ibn-e-Abi Talib Hospital for treatment of opioid use disorder using buprenorphine-assisted withdrawal. The clinical chart abstraction of patients’ files was made to provide the baseline situation of the patients, as well as treatment progress at discharge and one and three months post-discharge. Results: Among 12 adolescents, 8 (66.6%) were male and 4 (33.3%) were female. All patients reported crack heroin as their main drug of use. The mean maximum dose of buprenorphine in a day during hospital stay was 7.00 ± 2.00 mg in the range of 2 to 10 mg/d. The mean length of hospital stay was 14.66 ± 2.9 days. No serious adverse events were seen. Conclusions: This is the first report that provides data on the feasibility, effectiveness, and safety of inpatient buprenorphine-assisted treatment for vulnerable adolescents with opioid use disorder in Iran. Further studies are needed to investigate the safety and efficacy of withdrawal and maintenance treatment with buprenorphine in community settings.

Item Type: Article
Keywords: Opioid-Related Disorders; Adolescent; Buprenorphine; Treatment
Subjects: WM Psychiatry > WM 400-460.7 Therapies
Divisions: Education Vice-Chancellor Department > Faculty of Medicine > Departments of Clinical Sciences > Department of Psychiatric
Journal or Publication Title: International Journal of High Risk Behaviors and Addiction
Volume: 8
Number: 1
Identification Number: https://doi.org/10.5812/ijhrba.66470
ISSN: 2225-872x
Depositing User: خانم مهدیه رضائی پور
URI: http://eprints.zaums.ac.ir/id/eprint/3028

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