Repository of Research and Investigative Information

Repository of Research and Investigative Information

Zahedan University of Medical Sciences

Optimization of Aqueous and Alcoholic Extraction of Phenolic and Antioxidant Compounds From Caper (Capparis Spinosa L.) Roots Assisted by UltrasoundWaves

(2020) Optimization of Aqueous and Alcoholic Extraction of Phenolic and Antioxidant Compounds From Caper (Capparis Spinosa L.) Roots Assisted by UltrasoundWaves. Zahedan Journal of Research in Medical Sciences. ISSN e: 2383-2894

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Abstract

Background: Herbals are rich in effective compounds such as phenolic and antioxidant. Various methods are developed to extract these compounds, including Soxhlet, maceration, microwave, and ultrasound. The extraction method affects the quantity and quality of materials. Objectives: The current study aimed to investigate the effect of ultrasound in phenolic and antioxidants compounds extraction from Caper roots. Methods: Response surface methodology (RSM) and Box-Behnken design were used to optimize the two extraction parameters, including extraction time (10, 25, and 40 min) and ultrasound power (40%, 70%, 100 %) by aqueous and alcoholic solvents. Results: Based on the results, ultrasound power was more effective than the extraction time. A direct association was observed between ultrasound power and the extraction time with the total extraction. The optimum aqueous and alcoholic extraction condition for phenolic and antioxidant compounds extraction were as follow: extraction time 36 min and ultrasound power 91 percent. Total phenolic content was obtained 14.96mg/gwith aqueous solvent and 17.24mg/gwith alcoholic solvent, and IC50 was 52.17�g/mg with aqueous solvent and 40.20 �g/mg with alcoholic solvent. Conclusions: Overall, alcoholic extracts had more phenolic and antioxidant compounds than aqueous extracts.

Item Type: Article
Keywords: Capparis Spinosa, Phenolic Compounds, Antioxidant, Ultrasound
Subjects: QV Pharmacology > QV 310-325 Noble Gases. Oxygen. Antioxidants
QV Pharmacology > QV 600-666 Toxicology
Divisions: Education Vice-Chancellor Department > Faculty of Pharmacy > Department of Toxicology and Pharmacology
Journal or Publication Title: Zahedan Journal of Research in Medical Sciences
Journal Index: ISC, Not Index
Volume: 22
Number: 4
Publisher: Kowsarmedical
Identification Number: 0.5812/zjrms.100747
ISSN: e: 2383-2894
Depositing User: خانم دنیاداری مهدیه
URI: http://eprints.zaums.ac.ir/id/eprint/5002

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