Repository of Research and Investigative Information

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Zahedan University of Medical Sciences

Experimental and clinical studies on the effects of Portulaca oleracea L. and its constituents on respiratory, allergic, and immunologic disorders, a review

(UNSPECIFIED) Experimental and clinical studies on the effects of Portulaca oleracea L. and its constituents on respiratory, allergic, and immunologic disorders, a review. Phytotherapy Research. p. 30. ISSN 0951-418X

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Abstract

Various pharmacological effects for Portulaca oleracea were shown in previous studies. Therefore, the effects of P. oleracea and its derivatives on respiratory, allergic, and immunologic diseases according to update experimental and clinical studies are provided in this review article. PubMed/Medline, Scopus, and Google Scholar were searched using appropriate keywords until the end of December 2020. The effects of P. oleracea and its constituents such as quercetin and kaempferol on an animal model of asthma were shown. Portulaca oleracea and its constituents also showed therapeutic effects on chronic obstructive pulmonary disease and chronic bronchitis in both experimental and clinical studies. The possible bronchodilatory effect of P. oleracea and its ingredients was also reported. Portulaca oleracea and its constituents showed the preventive effect on lung cancer and a clinical study showed the effect of P. oleracea on patients with lung adenocarcinoma. In addition, a various constituents of P. oleracea including, quercetin and kaempferol showed therapeutic effects on lung infections. This review indicates the therapeutic effect of P. oleracea and its constituents on various lung and allergic disorders but more clinical studies are required to establish the clinical efficacy of this plant and its constituents on lung and allergic disorders.

Item Type: Article
Keywords: allergy and immunology disorders alpha-linolenic acid genistin kaempferol Portulaca oleracea quercetin respiratory disorders acute lung injury nf-kappa-b hydro-ethanolic extract airway smooth-muscle conjugated linoleic-acid guinea-pig in-vivo pulmonary-fibrosis oxidative stress medicinal-plants Pharmacology & Pharmacy
Page Range: p. 30
Journal or Publication Title: Phytotherapy Research
Journal Index: ISI
Identification Number: https://doi.org/10.1002/ptr.7268
ISSN: 0951-418X
Depositing User: مهندس مهدی شریفی
URI: http://eprints.zaums.ac.ir/id/eprint/5392

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